Welcome to our Cell Signalling Lab
Research in our laboratory is focused on defining eukaryotic signal transduction pathways, and investigating how mutations in components of these pathways can contribute to human diseases such as kidney disease and cancer. Our research team investigates questions related to these pathways using an interdisciplinary approach which includes modern mouse genetic tools, cell culture models, high-resolution microscopy, large-scale profiling techniques and clinical specimens.
Signal transduction is a central process in multicellular organisms that allows for the exchange of informational cues between and within cells. These cues are interpreted by organized networks of protein interactions inside the cell which regulate complex biochemical events, ultimately converting them into biological responses such as growth, migration, differentiation and survival. Cells have evolved a tremendous ability to selectively activate specific downstream pathways through the formation of distinct protein complexes. Understanding the molecular basis of these interactions is a significant challenge in biology, and it is of key importance in defining how specific mutations can lead to pathological conditions such as kidney disease and cancer.
Latest Lab News
- Sept 8, 2022 — Welcome Hayley, Una, and Erka!
Welcome to our new Masters students Erka and Una! Una completed her BSc here at UofG in Molecular Biology and Genetics, and completed her fourth year project in the Bendall lab. Erka joins us after completing her BSc in the University of Toronto.
- Jan 6, 2023 — Welcome back Cassandra!
Welcome back Cassandra (Cassie) Claussen to the Jones Lab for an MSc! While in the Molecular Biology and Genetics…
- Oct 31, 2022 — Pumpkin carving contest entry
The Jones Lab 2022 entry designed by one of our undergraduate project students Alice Wang! Spooky science!
- May 1, 2023 — Welcome Justin!
Welcome to Justin Chamberlain who was awarded an NSERC URA! In the fall, Justin will be returning to the…
- May 12, 2023 — Jones Lab at Guelph Neuroscience Day
Jones lab members Hyeyun Yang and Cassie Claussen presented posters at this year’s Neuroscience day.
