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Welcome to the Jones Lab

Welcome to our Cell Signalling Lab

Research in our laboratory is focused on defining eukaryotic signal transduction pathways, and investigating how mutations in components of these pathways can contribute to human diseases such as kidney disease and cancer. Our research team investigates questions related to these pathways using an interdisciplinary approach which includes modern mouse genetic tools, cell culture models, high-resolution microscopy, large-scale profiling techniques and clinical specimens. 

Signal transduction is a central process in multicellular organisms that allows for the exchange of informational cues between and within cells. These cues are interpreted by organized networks of protein interactions inside the cell which regulate complex biochemical events, ultimately converting them into biological responses such as growth, migration, differentiation and survival. Cells have evolved a tremendous ability to selectively activate specific downstream pathways through the formation of distinct protein complexes. Understanding the molecular basis of these interactions is a significant challenge in biology, and it is of key importance in defining how specific mutations can lead to pathological conditions such as kidney disease and cancer.

Latest Lab News

  • May 6, 2024 — Congratulations Hayley

    Congratulations to Hayley Smith for her very successful qualifying exam! Our newest PhD candidate passed her qualifying exam with flying colours.

  • May 1, 2024 — Welcome New Students

    The Jones Lab welcomes new undergrads Mathew Hibbert, joining the lab with a USRA scholarship, and Abby Vyn, joining with a CBS-SRA scholarship. We also welcome Nikoo Mansourian, joining us for a fourth-year project!

  • April 23, 2024— Congratulations Casey

    Congratulations to the new Dr. Casey Williamson on her extremely successful Doctoral defense!

  • April 18th, 2024 — Happy end of W24

    As another academic year comes to an end, the Jones lab celebrates with ice cream at the Boathouse! Even if it was almost freezing outside…

  • Mar 14th, 2024 – World Kidney Day

    World Kidney Day (WKD) is celebrated internationally every second Thursday in March to raise awareness of the importance of our kidneys. This year, the theme of WKD is: Kidney Health for All – Advancing equitable access to care and optimal medication practice.

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Latest Publications

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